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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP1
All Species:
7.88
Human Site:
S250
Identified Species:
19.26
UniProt:
Q92667
Number Species:
9
Phosphosite Substitution
Charge Score:
0.44
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92667
NP_003479.1
903
97342
S250
E
D
K
G
K
S
S
S
S
Q
V
V
G
P
V
Chimpanzee
Pan troglodytes
XP_001172270
903
97389
S250
E
D
K
G
K
S
S
S
S
Q
V
V
G
P
V
Rhesus Macaque
Macaca mulatta
XP_001105339
908
98058
S249
E
E
K
G
K
S
S
S
S
Q
V
G
P
V
Q
Dog
Lupus familis
XP_866604
861
92337
E236
A
P
L
G
G
A
G
E
K
G
K
G
S
P
P
Cat
Felis silvestris
Mouse
Mus musculus
O08715
857
92146
P239
G
E
E
V
S
H
G
P
P
Q
V
A
E
L
L
Rat
Rattus norvegicus
O88884
854
91729
P239
G
E
K
V
R
S
G
P
P
Q
V
D
E
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506373
818
86895
E225
S
E
S
N
E
K
I
E
Q
A
A
L
Q
I
I
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
NP_001027918
738
77887
E154
A
A
R
L
P
G
V
E
R
P
E
P
E
G
E
Fruit Fly
Dros. melanogaster
NP_572221
585
64889
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09285
867
96411
E231
K
T
V
E
I
H
T
E
T
E
E
T
D
H
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
91.7
74
N.A.
68.4
68.3
N.A.
50.3
N.A.
N.A.
N.A.
41.4
22.7
N.A.
23.1
N.A.
Protein Similarity:
100
98.7
93.5
80.8
N.A.
76.3
76.1
N.A.
60.5
N.A.
N.A.
N.A.
53.2
38.8
N.A.
40.3
N.A.
P-Site Identity:
100
100
66.6
13.3
N.A.
13.3
26.6
N.A.
0
N.A.
N.A.
N.A.
0
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
73.3
20
N.A.
33.3
46.6
N.A.
26.6
N.A.
N.A.
N.A.
6.6
0
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
0
0
10
0
0
0
10
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
20
0
0
0
0
0
0
0
0
0
10
10
0
0
% D
% Glu:
30
40
10
10
10
0
0
40
0
10
20
0
30
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
40
10
10
30
0
0
10
0
20
20
10
0
% G
% His:
0
0
0
0
0
20
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
10
% I
% Lys:
10
0
40
0
30
10
0
0
10
0
10
0
0
0
0
% K
% Leu:
0
0
10
10
0
0
0
0
0
0
0
10
0
20
20
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
20
20
10
0
10
10
30
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
50
0
0
10
0
10
% Q
% Arg:
0
0
10
0
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
0
10
0
10
40
30
30
30
0
0
0
10
0
0
% S
% Thr:
0
10
0
0
0
0
10
0
10
0
0
10
0
0
0
% T
% Val:
0
0
10
20
0
0
10
0
0
0
50
20
0
10
30
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _